DRCR - Protocol AC

Pathology: Diabetic Macular Edema (DME)

Description: Randomized Trial of Intravitreous Aflibercept versus Intravitreous Bevacizumab + Deferred Aflibercept for Treatment of Central Involved Diabetic Macular Edema

Study Objectives: To compare the efficacy of intravitreous aflibercept with intravitreous bevacizumab + deferred aflibercept if needed in eyes with CI DME and moderate vision loss

Principal Investigator: Dr. Blinder

Status: Open Enrollment


DRCR - Protocol AE

Pathology: Diabetic Macular Edema (DME)

Description: A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema

Study Objectives: This study is being conducted to assess the effects of photobiomodulation on CST compared with sham in eyes with central-involved DME and good vision. Photobiomodulation is irradiation by light in the 630-900 nanometer region of the spectrum.

Furthermore, this pilot study is being conducted to determine whether the conduct of a pivotal trial has merit based on an anatomic outcome and provide information on outcome measures needed to design a pivotal trial.

Principal Investigator: Dr. Blinder

Status: Open Enrollment


DRCR - Protocol AG

Pathology: Vitreomacular Traction (VMT)

Description: Randomized Clinical Trial Assessing the Effects of Pneumatic Vitreolysis on Vitreomacular Traction

Study Objectives: Eyes with idiopathic symptomatic vitreomacular traction (VMT) without a macular hole will be randomly assigned to 0.3-mL intraocular gas (C3F8) injection or sham injection to determine if pneumatic vitreolysis (PVL) is effective in releasing VMT.

Principal Investigator: Dr. Blinder

Status: Enrollment - Currently Suspended