General Information

The Retina Institute participates in numerous national studies recognizing that medical research lies at the core of clinical advancements. These studies are used to assist in the diagnosis, prevention and treatment of various retinal diseases. Clinical trials help establish if new treatments, new drugs, or new surgical procedures are safe and effective.

Participation in a clinical trial is an important decision and should be discussed with a physician. Enrollment in a study possibly means receiving the newest management and care for a disease or illness. Participants often join to help others with the same condition by assisting researchers in their efforts to find better treatments. These trials offer future hope for many people with sight-threatening conditions.

Clinical trials in the U.S. must follow strict protocol and be registered with The National Institute of Health (NIH). A listing of these studies can be found in the clinicaltrials.gov database.

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CURRENT STUDIES

Study Title: DRCR AB

Enrollment Status: Closed

Pathology: Proliferative Diabetic Retinopathy (PDR)

Description: Intravitreous Anti-VEGF vs. Prompt Vitrectomy for Vitreous Hemorrhage from Proliferative Diabetic Retinopathy (Protocol AB)

Primary Investigator: Dr. Blinder

Co-Investigators: Dr. Krummenacher, Dr. Dang

 

Study Title: DRCR AC

Enrollment Status: Currently Enrolling

Pathology: Diabetic Macular Edema (DME)

Description: Randomized Trial of Intravitreous Aflibercept vs. Intravitreous Bevacizumab + Deferred Aflibercept for Treatment of Central-Involved Diabetic Macular Edema

Primary Investigator: Dr. Blinder

Co-Investigators: Dr. Krummenacher, Dr. Dang

 

Study Title: DRCR TX

Enrollment Status: Closed, Extension of DRCR T

Pathology: Diabetic Macular Edema (DME)

Description: A Comparative Effectiveness Study of Intravitreal Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema

Primary Investigator: Dr. Blinder

Co-Investigators: Dr. Smith, Dr. Krummenacher

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current studies

Study Title: DRCR V

Enrollment Status: Closed

Pathology: Diabetic Macular Edema (DME)

Description: Treatment for Central-Involved Diabetic Macular Edema in Eyes with Very Good Visual Acuity

Primary Investigator: Dr. Blinder

Co-Investigators: Dr. Smith, Dr. Krummenacher

 

Study Title: SAPPHIRE

Enrollment Status: Closed

Pathology: Branch Retinal Vein Occlusion (BRVO), Central Retinal Vein Occlusion (CRVO)

Description: SAPPHIRE: A Randomized, Masked, Controlled Trial to Study the Safety and Efficacy of Suprachoroidal CLS-TA in Conjuction with Intravitreal Aflibercept in Subjects with Retinal Vein Occlusion

Primary Investigator: Dr. Blinder

Un-Masked Investigators: Dr. Thomas, Dr. Blinder

Masked Investigators: Dr. Parikh, Dr. Banda, Dr. Ansari, Dr. Blackorby

 

Study Title: SCORE 2

Enrollment Status: Closed in Follow-up Stages

Pathology: Retinal Vein Occlusion (RVO)

Description: Study of Comparative Treatments for Retinal Vein Occlusion 2

Primary Investigator: Dr. Blinder

Sub-Investigators: Dr. Smith

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current studies

Study Title: GR39821

Enrollment Status: Closed

Pathology: Geographic Atrophy (GA)

Description: A Phase I, Multi-center, Open-label, Single-dose, Dose-escalation and Multiple-dose Study of the Safety, Tolerability, Pharmacokinetics, and Immunogencity of Intravitreal Injections of FHTR2163 in Patients with Geographic Atrophy Secondary to Age-Related Macular Degeneration

Primary Investigator: Dr. Blinder

Sub-Investigators: Dr. Parikh, Dr. Banda, Dr. Ansari, Dr. Blackorby, Dr. Smith, Dr. Dang

 

Study Title: My Retina Tracker - Genetic Testing Study

Enrollment Status: Currently Enrolling per Physician Referral

Pathology: Retinitis Pigmentosa (RP)

Description: Saliva Sample.  Any Doctor Can Send Patients into this Study for Genetic Testing.