Upcoming Clinical Trials

  • CTX114-CS101/CHARACTER BIOSCIENCES

Pathology: Dry Age-Related Macular Degeneration

Description: A phase1, open-label clinical study to evaluate the safety, tolerability, and pharmacokinetics of CTX-114 injection in subjects with dry age-related macular degeneration

 

  • DRCR AP

Pathology: Proliferative Diabetic Retinopathy

Description: A randomized clinical trial evaluating combination Faricimab + PRP versus vitrectomy + endolaser for treatment of proliferative diabetic retinopathy

  • EYE-RES-103/BOROLO

Pathology: Diabetic Macular Edema

Description: A randomized, double-masked, multicenter, 3-arm pivotal phase 2/3 study to evaluate the efficacy and safety of intravitreal eye 103 compared with intravitreal ranibizumab (0.5 mg) in participants with diabetic macular edema

 

  • ONL1204-GA-002

Pathology: Geographic Atrophy

Description: A Phase 2 Multicenter, Randomized, Double-masked, Sham-controlled, Reference-arm Study to Evaluate Efficacy and Safety of ONL1204 in Patients with Geographic Atrophy (GA) associated with Age-related Macular Degeneration (AMD)

 

  • PEAK AND PINNACLE

Pathology: Macular Edema Secondary to Inflammation

Description: A randomized, double-masked, sham-controlled, multicenter, phase 3 study to evaluate the efficacy and safety of intravitreal Tabirafusp Alfa (KSI-101) in participants with macular edema secondary to inflammation